Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction
نویسندگان
چکیده
منابع مشابه
Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction.
An unusual reaction with Grubbs' catalyst during the synthesis of bridged epothilones yielded five-membered internal lactones instead of the expected metathesis products. Three of the lactones have activities comparable to epothilone D.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2010
ISSN: 1359-7345,1364-548X
DOI: 10.1039/b926174e